Goals from James Vaughan and Mark Ellis saw Accrington Stanley suffer a 2-1 defeat to Tranmere Rovers.
Vaughan's early goal gave the visitors the lead at the break, with Ellis then grabbing a second goal from close range on 78 minutes.
An own goal from Alex Woodyard halved the deficit four minutes later, but Harvey Rodgers then received a second yellow card for a foul on Vaughan in added time.